Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Quantification of nucleic acids

¹Department of Pathology, University of Michigan, Ann Arbor, USA.

Clinics in Laboratory Medicine

|March 1, 1997

Summary

This summary is machine-generated.

Accurate quantification of nucleic acids is crucial in clinical labs. This article reviews methods for measuring total and specific nucleic acid concentrations for various applications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Genotyping of apolipoprotein e.

Methods in molecular medicine·2011

Same author

Molecular genetic pathology: an exam, finally.

Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology·2002

Same author

Commentary: molecular analysis of congenital adrenal hyperplasia in a newborn screening program.

Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology·2001

Same author

An overview of molecular diagnosis of steroid 21-hydroxylase deficiency.

The Journal of molecular diagnostics : JMD·2001

Same author

Evaluation of chimerism in DNA samples by PCR amplification of D1S80 with detection by capillary electrophoresis.

Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology·2000

Same author

Association of the prothrombin G20210A mutation with factor V Leiden in a midwestern American population.

American journal of clinical pathology·2000

Same journal

Advances in Hemostasis Laboratory Testing.

Clinics in laboratory medicine·2026

Same journal

Extracellular Vesicles in Hemostasis.

Clinics in laboratory medicine·2026

Same journal

Thrombin Generation Assay: Ready for Prime Time.

Clinics in laboratory medicine·2026

Same journal

Viscoelastic Testing for the Laboratorian: Recent Advances and Practical Advice.

Clinics in laboratory medicine·2026

Same journal

Practical Recommendations for Harmonization of Hemostasis Testing Across Hospital Sites.

Clinics in laboratory medicine·2026

Same journal

The Role of Hypoxia in Vascular Endothelial Dysfunction and Venous Thromboembolism.

Clinics in laboratory medicine·2026

See all related articles

Area of Science:

Clinical chemistry
Molecular diagnostics
Biotechnology

Background:

Nucleic acid quantification is increasingly vital in clinical laboratory settings.
Techniques are used beyond total concentration measurements, including microbial enumeration, gene expression analysis, and gene dosage assessments.

Purpose of the Study:

To provide a comprehensive overview of current methodologies for nucleic acid measurement.
To cover techniques for both total and specific nucleic acid quantification.

Main Methods:

Review of existing literature on nucleic acid quantification techniques.
Categorization of methods based on their application (total vs. specific quantification).

Main Results:

Related Experiment Videos

Established methods exist for routine total nucleic acid concentration measurements.

Specialized quantitative techniques are available for specific applications like microbial detection and gene analysis.

Conclusions:

A range of methodologies are available for precise nucleic acid quantification in clinical diagnostics.
Understanding these methods is key for accurate clinical laboratory results and applications.