Related Experiment Videos
[Diastolic dysfunction of the left ventricle: from physiopathology to treatment]
H Karpuz1, L Kappenberger, X Jeanrenaud
1Division de Cardiologie, Centre Hospitalier Universitaire Vaudois, Lausanne.
Insights
Left ventricular diastolic dysfunction is a primary cause of cardiac failure, often appearing earliest in chronic conditions. Understanding this dysfunction is key to diagnosing and treating heart failure effectively.
Area of Science:
- Cardiology
- Heart Failure Research
Abstract:
Our understanding of cardiac failure has greatly changed over the last 15 years. Left ventricular diastolic dysfunction, which is now recognised as one of the primary causes of certain types of cardiac failure (1). Abnormal left ventricular diastolic function is the common determinant and indeed the earliest sign of all chronic left ventricular failures whether systolic left ventricular dysfunction is associated with it or not (2). In this paper, we review the basis of diastolic dysfunction and its impact on diagnosis and treatment of cardiac failure.