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Aging processes, DNA damage, and repair

B A Gilchrest1, V A Bohr

  • 1Department of Dermatology, Boston University School of Medicine, Massachusetts 02118, USA.

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
|April 1, 1997
PubMed
Summary
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This conference explored aging, DNA damage, and repair. Key discussions linked oxidative damage to cancer and aging, highlighting research across various models.

Area of Science:

  • Gerontology
  • Molecular Biology
  • Genetics

Background:

  • The FASEB Summer Research Conference convened experts in aging and DNA repair.
  • Research spans cellular gerontology, model organisms (yeast, nematodes), and fundamental DNA mechanisms.

Framework:

  • Discussions covered classic cellular gerontology, yeast and nematode aging models, and fundamental DNA repair processes.
  • A keynote address by Dr. Bruce Ames underscored the established links between oxidative damage, cancer, and aging.

Implementation:

  • The meeting featured eight platform sessions, a poster discussion, and a special presentation.
  • Attendees included senior and junior investigators from diverse research backgrounds.

Implications:

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  • The conference provided a comprehensive overview of current research at the intersection of aging and DNA integrity.
  • Findings contribute to understanding the molecular basis of aging and age-related diseases.