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Epidemiology of interstitial cystitis
1National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892-6600, USA.
Urology
|May 1, 1997
Summary
Interstitial cystitis (IC) prevalence estimates vary widely due to inconsistent diagnostic criteria. Further research is needed to understand this chronic condition and its demographics.
Area of Science:
- Urology
- Epidemiology
- Public Health
Background:
- Interstitial cystitis (IC) is a chronic condition characterized by voiding symptoms.
- Limited reliable data exists regarding the etiology, risk factors, and true population prevalence of IC.
Purpose of the Study:
- To review the current understanding of interstitial cystitis (IC) population prevalence.
- To describe the demographic characteristics of individuals diagnosed with IC.
Main Methods:
- Review of three published population prevalence studies for IC.
- Analysis of changes in diagnostic criteria for IC over time.
- Identification of key epidemiologic considerations for future IC research.
Main Results:
- Prevalence estimates for IC vary significantly across studies, ranging from 10 to 510 cases per 100,000 individuals.
- Discrepancies in prevalence are likely due to differing case definitions and diagnostic methodologies.
- Studies indicate a female predominance in IC patients, with symptom onset typically in middle age.
Conclusions:
- There is a need for standardized diagnostic criteria and rigorous epidemiologic methods in IC research.
- Further investigation is required to address unanswered questions regarding IC.
- Epidemiologic consultation during study design is recommended for future IC research.