Related Experiment Video
Updated: Aug 11, 2026

Manipulation of Epileptiform Electrocorticograms (ECoGs) and Sleep in Rats and Mice by Acupuncture
Published on: December 22, 2016
Season of birth: aetiological implications for epilepsy
M Procopio1, P K Marriott, P Williams
1Royal London Hospital (St. Clement's), UK.
Abstract:
In most cases of epilepsy it is not possible to reach an aetiological diagnosis. Recent research points to a pre-perinatal disruption of the neurodevelopment as being the cause of at least some of these epilepsies of unknown aetiology. The object of this study was to corroborate this hypothesis from an epidemiological perspective and identify the most likely candidates for causes of this damage. The approach used was an analysis of the seasonal pattern of births in a large sample of epileptic patients discharged from NHS hospitals in England and Wales. The results illustrated that the seasonality of the births in the epileptic sample was significantly different from that of the general population, with an excess of patients born in December and January and a deficit of those born in September. This "seasonality' was present only in the patients born before the late 1950s. These results are suggestive of the existence of an aetiological factor for epilepsy with a seasonal presence in the environment and which is epileptogenic when acting in the pre-perinatal period. Prenatal infections, obstetric complications and nutrititional deficiencies are amongst the hypotheses developed on the nature of this agent(s).
More Related Videos
09:57Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
08:04Identification and Classification of Position-specific GABAA Receptor Subunit Missense Variants for Their Role In Hippocampal Pyramidal Neurons
Published on: June 6, 2025
Related Concept Videos
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Seizures: Classification
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Encephalitis l: Introduction
Seizures l: Introduction
Seizures ll: Types
Epilepsy ll: Types