Nutrition management in a pregnant comatose patient

Major intracranial injury or disease during pregnancy resulting in a comatose state presents unique and complex management challenges. Our patient is a 34-year-old woman who suffered a closed-head injury associated with spousal abuse at 22 weeks' gestation. This injury resulted in a large right frontoparietal hematoma that was subsequently evacuated via a right frontotemporal craniotomy 5 days after the injury. She remained in a vegetative state postoperatively. Aggressive nutrition support was provided with enteral feedings through a nasoduodenal feeding tube. Mild oligohydramnios was detected at 30 weeks' gestation and was subsequently determined to be due to preterm premature rupture of membranes. She was managed until 33 weeks' gestation, when signs of chorioamnionitis were noted. She then underwent a primary cesarean delivery and was delivered of an appropriate-for-gestational-age 2150-g viable male infant. The patient had progressive improvement in her mental status with occupational and physical therapy and was discharged on the 29th postpartum day. This case presents the nutrition and medical challenges of maintaining adequate maternal and fetal health in a pregnant comatose patient.