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Related Experiment Videos

Frusemide-induced bullous pemphigoid

B N Panayiotou1, M V Prasad, M N Zaman

  • 1Department of Elderly Care, Manor Hospital, Walsall, West Midlands.

The British Journal of Clinical Practice
|January 1, 1997
PubMed
Summary
This summary is machine-generated.

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Bullous pemphigoid is a rare side effect of frusemide. Early recognition and drug withdrawal are crucial for resolving leg blistering and ulceration in elderly patients.

Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Bullous pemphigoid (BP) is an autoimmune blistering disease.
  • Frusemide (furosemide) is a common diuretic used for heart failure.

Observation:

  • Two elderly patients with heart failure developed bullous pemphigoid during frusemide therapy.
  • The link between frusemide and bullous pemphigoid was not initially recognized, leading to prolonged treatment.

Findings:

  • Continued frusemide administration resulted in persistent leg blistering and ulceration in both patients.
  • Complete resolution of skin lesions occurred upon discontinuation of frusemide.

Implications:

  • Frusemide-induced bullous pemphigoid, though uncommon, is a significant consideration in patients presenting with blistering disorders.

Related Experiment Videos

  • Prompt drug withdrawal can prevent prolonged morbidity in elderly patients, particularly those with comorbidities like heart failure.