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Two specific and simple methods for genotyping of the paraoxonase/arylesterase A/B polymorphism
1Departmeng of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Genetic Analysis : Biomolecular Engineering
|March 1, 1997
Abstract:
We developed an amplification refractory mutation system (ARMS) and mutagenically separated PCR (MS-PCR) assays for genotyping of the paraoxonase/arylesterase (PONA) A/B polymorphism as practical, reliable, and more economic alternatives to the conventional restriction fragment length polymorphism (RFLP) technique for detection of this mutation.