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[The treatment of appendicular peritonitis complicated by septic shock in childhood]
Insights
This study on pediatric appendicular peritonitis and septic shock found that complex treatment, including controlled laparostomy and artificial pulmonary ventilation, significantly reduced mortality rates from 54.5% to 11.1%.
Area of Science:
- Pediatric Surgery
- Critical Care Medicine
- Infectious Diseases
Background:
- Appendicular peritonitis in children can lead to life-threatening septic shock.
- Septic shock presents a significant challenge in pediatric surgical cases.
- High mortality rates are associated with complicated appendicular peritonitis and septic shock.
Purpose of the Study:
- To evaluate the effectiveness of a comprehensive treatment protocol for pediatric appendicular peritonitis complicated by septic shock.
- To analyze the impact of specific interventions on reducing mortality in this patient group.
Main Methods:
- Analysis of treatment outcomes for 39 children aged 1-14 years with appendicular peritonitis and septic shock.
- Implementation of a complex pathogenetic treatment strategy.
- Inclusion of controlled laparostomy, artificial pulmonary ventilation (pre- and post-operative), and afferent methods.
Main Results:
- The study demonstrated a substantial decrease in mortality rates.
- Mortality decreased from 54.5% to 11.1% in the treated cohort.
- The integrated treatment approach proved effective in improving survival.
Conclusions:
- A complex pathogenetic treatment strategy is highly effective for pediatric appendicular peritonitis with septic shock.
- Controlled laparostomy and artificial pulmonary ventilation are crucial components of this treatment.
- Afferent methods, when used adjunctively, contribute to improved patient outcomes and survival.
Abstract:
The article presents an analysis of results of treatment of 39 children from 1 to 14 years of age with diagnosis of appendicular peritonitis complicated by septic shock. It was shown that complex pathogenetic treatment with controlled laparostomy, necessary compulsory or subsidiary artificial pulmonary ventilation before and after operative intervention, associated use of afferent methods allowed to decrease the number of lethal outcomes from 54.5 to 11.1%.