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[The clinico-electroneuromyographic characteristics of acute inflammatory polyneuropathies in children]
Insights
Electroneuromyography identified distinct axonal and demyelinating patterns in pediatric acute polyneuropathies. These patterns differentiated Guillain-Barré syndrome and diphtheritic PNP, impacting disease severity and recovery.
Area of Science:
- Pediatric Neurology
- Clinical Electrophysiology
Abstract:
Clinical electroneuromyographic examination (ENME) was carried out in 59 children at the age of 1-12 years with acute demyelinating polyneuropathies (PNP). The patients were divided into two groups, namely: 24 children with Guillain-Barré [correction of Giyenne-Barret] syndrome (the first) and 35 ones with diphtheritic PNP (the second group). The main clinical symptoms were investigated in each group. As a result of ENME investigation the axonal and demyelinating types of PNP's beginning were identified. They were distinguished both by severity of course and by rate of restoration. Diphtheritic PNP was characterized by demyelinating type of pathology rise with addition of axonal component in severe cases. The conduction through the additional nerves was investigated to prognose the development of bulbar disorders in PNP.
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