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Multiple leiomyosarcoma of the stomach
R B Colovic1, M Colovic, D Ciganovic
1Institute for Digestive Diseases, Clinical Center of Serbia First Surgical Clinic Belgrade, Yugoslavia.
Hepato-Gastroenterology
|March 1, 1997
Summary
Multiple gastric leiomyosarcomas, a rare condition, were diagnosed in a 40-year-old female. Surgical removal led to an uneventful recovery, with the patient remaining symptom-free for nine months.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Leiomyosarcoma is the second most common non-epithelial malignant gastric tumor, typically presenting as a solitary lesion.
- Multiple gastric leiomyosarcomas are exceptionally rare, with only three prior reported cases in medical literature.
Observation:
- A 40-year-old female presented with epigastric pain, nausea, diarrhea, weight loss, and melena.
- Diagnostic evaluation revealed multiple gastric lesions, confirmed intraoperatively as 11 submucosal or subserosal leiomyosarcomas ranging from 0.5 to 6 cm.
- Metastases were identified in regional lymph nodes along the gastric curvatures, but not in distant organs.
Findings:
- Histological examination confirmed leiomyosarcoma in all 11 gastric lesions.
- The patient underwent total gastrectomy with Roux-en-Y esophagojejunostomy.
Implications:
- This case expands the understanding of rare multifocal gastric leiomyosarcoma presentations.
- Successful surgical management of multiple gastric leiomyosarcomas offers a potential treatment pathway for this rare malignancy.
- Further research into the etiology and optimal management of multifocal gastric leiomyosarcoma is warranted.