Progress in pediatric liver transplantation--the Birmingham experience
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Updated: Nov 1, 2026

Technique of Porcine Liver Procurement and Orthotopic Transplantation using an Active Porto-Caval Shunt
Published on: May 7, 2015
D Talbot1, O A Achilleos, B K Gunson
1Liver and Hepatobiliary Unit, Queen Elizabeth Hospital, Birmingham, England.
Insights
Birmingham, UK pediatric liver transplantation has evolved significantly since 1983. Over 200 liver grafts have been successfully placed in children, achieving an excellent survival rate exceeding 80%.
Area of Science:
- Hepatology
- Pediatric Surgery
- Transplantation Medicine
Background:
- The Birmingham, UK center has a long-standing history in pediatric liver transplantation.
- Pediatric liver transplantation is a critical intervention for end-stage liver disease in children.
Purpose of the Study:
- To detail the evolution and outcomes of pediatric liver transplantation at a major UK center.
- To analyze the cumulative experience and current survival rates.
Main Methods:
- Retrospective analysis of all pediatric liver transplants performed at the Birmingham center.
- Data collection from 1983 to the present, encompassing patient demographics, graft details, and outcomes.
Main Results:
- A total of 200 liver grafts were transplanted into 168 pediatric patients.
- The patient cohort included children under 17 years of age.
- Current patient survival rates exceed 80%.
Conclusions:
- The Birmingham center has established a robust and successful program for pediatric liver transplantation.
- High survival rates demonstrate the efficacy and advancement of pediatric liver transplant procedures over decades.
Abstract:
This report describes the evolution of the Birmingham, UK experience with pediatric liver transplantation from 1983 to present. Two hundred liver grafts were placed in 168 children less than 17 years of age. The current survival rate exceeds 80%.
