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Related Experiment Videos

Alarm treatment: influence on functional bladder capacity

A F Hansen1, T M Jørgensen

  • 1International Enuresis Research Centre, Skejby Hospital, University Hospital of Aarhus, Denmark.

Scandinavian Journal of Urology and Nephrology. Supplementum
|January 1, 1997
PubMed
Summary

Alarm treatment effectively increases nocturnal bladder capacity in children with monosymptomatic nocturnal enuresis. Longer treatment durations may yield better results for enuresis alarm therapy.

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Area of Science:

  • Pediatrics
  • Urology
  • Sleep Medicine

Background:

  • Monosymptomatic nocturnal enuresis (MNE) is a common condition in children.
  • Alarm treatment is a recognized therapy for MNE, but optimal duration and efficacy indicators require further study.

Purpose of the Study:

  • To evaluate the efficacy of alarm treatment for children with MNE.
  • To identify reliable indicators of alarm treatment success.
  • To determine the optimal duration for alarm treatment.

Main Methods:

  • Home recordings were used to monitor children with MNE undergoing alarm treatment for 6 weeks.
  • Vasopressin day/night ratios were analyzed as a potential indicator of treatment success.
  • Measurements included nocturnal bladder capacity, daytime bladder capacity, sleep patterns, vasopressin secretion, nocturnal urine output, and pelvic floor activity.

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Main Results:

  • Alarm treatment significantly increased nocturnal bladder capacity in children with MNE.
  • Vasopressin day/night ratios were identified as a good indicator of alarm treatment success.
  • No significant effects were observed on daytime bladder capacity, sleep patterns, vasopressin secretion, nocturnal urine output, or pelvic floor activity.

Conclusions:

  • Alarm treatment is effective in improving nocturnal bladder capacity for MNE.
  • Vasopressin day/night ratios can indicate treatment success, but serial plasma measurements are impractical for routine clinical use.
  • A treatment duration of 2 months may be more effective than the 6 weeks studied for achieving successful outcomes in enuresis alarm therapy.