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Related Experiment Videos

The umbilical pump: a contributor to twin-twin transfusion

T H Strong1

  • 1Phoenix Perinatal Associates, Good Samaritan Regional Medical Center, Arizona, USA.

Obstetrics and Gynecology
|May 1, 1997
PubMed
Summary

Umbilical vascular coiling may act as a pump. Higher coiling in recipient twins suggests a role in twin-twin transfusion syndrome development.

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Area of Science:

  • Perinatology
  • Fetal Medicine
  • Reproductive Biology

Background:

  • Umbilical vascular coiling is hypothesized to facilitate placental venous return.
  • The umbilical coiling index (UCI) quantifies vascular coiling density.

Observation:

  • A prospective study evaluated three twin gestations with twin-twin transfusion syndrome.
  • Umbilical cords and birth weights of donor and recipient twins were analyzed.
  • UCI was calculated by dividing the number of vascular coils by cord length (cm).

Findings:

  • Recipient twins were significantly larger than donor twins.
  • Recipient twins exhibited an umbilical coiling index at least double that of their donor counterparts.
  • Differential umbilical vascular coiling densities were observed between monochorionic twins.

Implications:

  • Variations in umbilical vascular coiling may contribute to the development of twin-twin transfusion syndrome.
  • Further research into the biomechanical role of umbilical coiling is warranted.
  • This finding may inform future diagnostic or therapeutic strategies for high-risk twin pregnancies.

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