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Trisomy among fetuses with noncoiled umbilical blood vessels
1Division of Maternal Fetal Medicine, Good Samaritan Regional Medical Center, Phoenix, Arizona, USA.
Objective:
To examine the relationship between trisomy and neonates with noncoiled umbilical blood vessels.
Study Design:
The incidence of and risk factors for trisomy were evaluated among 48 consecutive, live-born neonates with noncoiled umbilical vessels.
Results:
Four cases (8.3%) of trisomy were identified. One case of mosaicism was also noted (2.1%). In no case was noncoiling of the umbilical vessels the only identifiable risk factor. The remaining 43 infants (89.6%) were phenotypically normal, although not all underwent karyotype analysis.
Conclusion:
Noncoiled umbilical blood vessels alone do not appear to represent an independent risk factor for trisomy. Rather, identification of noncoiled blood vessels should prompt a thorough search for other abnormalities.