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Naproxen toxicosis in a puppy
1Wheat Ridge Animal Hospital, Wheat Ridge CO 80033, USA.
Veterinary and Human Toxicology
|June 1, 1997
Summary
Naproxen (ALLEVE) toxicosis in a puppy caused melena, lethargy, and vomiting. Prompt veterinary care, including a blood transfusion and gastroprotectants, led to the puppy's recovery.
Area of Science:
- Veterinary Medicine
- Toxicology
- Pharmacology
Background:
- Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), is commonly used for pain relief.
- Accidental ingestion of human medications in pets can lead to toxicosis.
- Puppies are particularly vulnerable to adverse drug reactions due to their developing physiology.
Observation:
- A young canine ingested 220 mg of naproxen over four days.
- Clinical manifestations included gastrointestinal bleeding (melena), reduced activity (lethargy), and emesis (vomiting).
Findings:
- The puppy presented with signs consistent with NSAID-induced gastrointestinal ulceration and potential anemia.
- Laboratory findings indicated anemia, necessitating a blood transfusion.
- Treatment focused on managing the acute toxic effects and supporting the patient's recovery.
Implications:
- This case highlights the critical importance of secure storage of human medications to prevent accidental pet ingestion.
- Veterinarians should consider naproxen toxicosis in puppies presenting with compatible clinical signs.
- Prompt and aggressive supportive care is crucial for managing NSAID toxicosis in juvenile animals.