Related Experiment Video
Updated: Jul 17, 2026
Using Confocal Analysis of Xenopus laevis to Investigate Modulators of Wnt and Shh Morphogen Gradients
Published on: December 14, 2015
Identification and characterization of MARCKS in Xenopus laevis
N Ali1, L J Macala, J P Hayslett
1Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Abstract:
MARCKS proteins are widely distributed in mammalian cells and subserve an important role as probes in the examination of signal transduction processes because they are specific endogenous phosphoreceptors for activated protein kinase C. Experiments were performed to determine whether MARCKS proteins are present in amphibia and to show their usefulness as substrates for stimulated PKC activation, using cultured renal epithelial cells (A6) derived from Xenopus laevis as an experimental model.
