Confirmatory factor analyses of the Anxiety and Depression content scales of the MMPI-2

A sample of 408 patients with substance use disorders was equally divided into derivation and cross-validation samples. All patients had taken the MMPI-2. Exploratory factor analyses of MMPI-2 item data in the derivation sample permitted construction of latent variable measurement models for the Anxiety (ANX) and Depression (DEP) content scales. The 2-factor models for ANX consisted of Trait Anxiety and Worry, and the 3-factor model for DEP contained factors of Trait Depression, Hopelessness, and Self-Depreciation. Confirmatory factor analyses in cross-validation demonstrated a good fit for both models and for their combination in a 5-factor measurement model. Latent variable correlations in the 5-factor model helped explain the high correlation and low discriminant validity of ANX and DEP.