[Cu(II) complexes with biomacromolecules. The use of Cu(II) ions as a structural spin label]

Complexes of Cu(II) ions with globular proteins (human serum albumin, bovine serum albumin, egg albumin, lisozim and DNA) have been studied using the ESR method. It was shown that Cu(II) ions may be use as structural "spin-label" to study conformational dynamics of macromolecules, including structural transition in biopolymers.