Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Idiopathic eosinophilia]

R M Trüeb1

  • 1Dermatologische Klinik, Universitätsspital, Zürich.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|March 1, 1997
PubMed
Summary
This summary is machine-generated.

Eosinophilia, an excess of eosinophils, is linked to various inflammatory diseases. Understanding eosinophil regulation offers new therapeutic targets for these conditions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pseudo-Fringe sign in frontal fibrosing alopecia-like cutaneous lupus erythematosus.

Journal of the European Academy of Dermatology and Venereology : JEADV·2022
Same author

Dystrophic calcinosis of the scalp from artificial hair implants: treatment with sodium metabisulfite.

Journal of the European Academy of Dermatology and Venereology : JEADV·2022
Same author

Minoxidil-induced hypertrichosis in a breastfed infant.

Journal of the European Academy of Dermatology and Venereology : JEADV·2021
Same author

Prepubertal pattern hair loss.

Clinical and experimental dermatology·2021
Same author

Comment on: folliculitis decalvans and lichen planopilaris phenotypic spectrum: a case report of two paediatric cases.

Journal of the European Academy of Dermatology and Venereology : JEADV·2021
Same author

Male frontal fibrosing alopecia: study of 35 cases and association with sunscreens, facial skin and hair care products.

Journal of the European Academy of Dermatology and Venereology : JEADV·2021
Same journal

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Viral infections of the skin].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Viral exanthems in children].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Erratum to: Digital health applications and data protection].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Virus-induced exanthems in returning travellers].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Venous ulcus cruris-Surgical treatment].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
See all related articles

Area of Science:

  • Immunology
  • Hematology

Context:

  • Peripheral and tissue eosinophilia are hallmarks of diverse inflammatory syndromes, including multisystem diseases like idiopathic hypereosinophilic syndrome (IHS) and localized eosinophilic conditions.
  • These syndromes involve vasculitis or non-vasculitic tissue damage, potentially leading to fibrosis.
  • The pathogenic role of eosinophils is evident from their activation and degranulation at injury sites.

Purpose:

  • To explore the association between eosinophilia and inflammatory syndromes.
  • To elucidate the mechanisms of eosinophil recruitment and localization in tissue inflammation.
  • To highlight the potential for targeted therapies based on improved understanding of eosinophil regulation.

Summary:

  • Eosinophilia, characterized by elevated eosinophil counts in blood and tissues, is associated with numerous inflammatory conditions.

Related Experiment Videos

  • Idiopathic hypereosinophilic syndrome (IHS) is a multisystem disorder, while other idiopathic eosinophilic syndromes may be tissue-limited with a better prognosis.
  • Eosinophil recruitment involves cytokines, adhesion molecules, and chemoattractants, with IL-5 playing a key role, as demonstrated in transgenic mouse models.

    • Impact:

    • Advances in understanding eosinophil biology and cytokine regulation pave the way for novel therapeutic strategies.
    • Targeted manipulation of eosinophil responses could lead to improved treatments for eosinophilic inflammatory diseases.
    • This research contributes to the broader field of immunopathology and the development of precision medicine approaches.