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[ABO compatibility and isoimmune neonatal thrombopenia]
Abstract:
25 families with serologically documented isoimmune neonatal thrombopenia were investigated for ABO-antigens of mother and child. In all cases mother and child were ABO-compatible. It is concluded that feto-maternal ABO-compatibility is a prerequisite for the development of isoimmune neonatal thrombopenia; hence, platelets must have ABO-antigens or be covered by soluble ABO-antigens.