Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Glucose versus lactated Ringer's solution during pediatric cardiac surgery

A Aouifi1, J Neidecker, C Vedrinne

  • 1Service d'Anesthésie-Réanimation Chirurgicale, Hopital Cardiovasculaire et Pneumologique L Pradel, Lyon, France.

Journal of Cardiothoracic and Vascular Anesthesia
|June 1, 1997
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diagnostic accuracy of a calibrated abdominal compression to predict fluid responsiveness in children.

British journal of anaesthesia·2018
Same author

[Indications of lung transplantation: Patients selection, timing of listing, and choice of procedure].

Revue de pneumologie clinique·2015
Same author

Resolution of acquired von Willebrand syndrome after transcatheter aortic valve implantation through a left transcarotid approach.

International journal of cardiology·2014
Same author

An attempt to validate the modification of the American-European consensus definition of acute lung injury/acute respiratory distress syndrome by the Berlin definition in a university hospital.

Intensive care medicine·2013
Same author

[Anaesthetic approach of paediatric pulmonary hypertension].

Annales francaises d'anesthesie et de reanimation·2012
Same author

[Venous air emboli in a 4 year old child].

Annales francaises d'anesthesie et de reanimation·2012

Glucose-free fluids during pediatric cardiac surgery risk hypoglycemia. Moderate intraoperative glucose infusion is safe and prevents dangerous low blood sugar levels in children undergoing heart repair.

Area of Science:

  • Pediatric Cardiac Surgery
  • Anesthesiology
  • Metabolic Regulation

Background:

  • Intraoperative fluid composition in pediatric cardiac surgery is debated.
  • The impact of glucose-containing fluids on blood glucose and insulin levels requires clarification.

Purpose of the Study:

  • To compare the effects of glucose versus glucose-free fluid infusions on blood glucose and insulin levels.
  • To evaluate the safety and efficacy of intraoperative glucose administration in pediatric cardiac surgery.

Main Methods:

  • Prospective, randomized, blinded study in a cardiovascular university center.
  • Forty non-diabetic children (4-10 kg) undergoing cardiac surgery with cardiopulmonary bypass.
  • Comparison of lactated Ringer's solution versus 5% glucose infusion at 3 mL/kg/h.

Related Experiment Videos

Main Results:

  • Three patients receiving glucose-free fluids experienced severe hypoglycemia before cardiopulmonary bypass.
  • Blood glucose levels increased post-cardiopulmonary bypass in both groups, with minimal differences.
  • No patient exhibited hyperglycemia exceeding 239 mg/dL.

Conclusions:

  • Glucose withdrawal during pediatric cardiac surgery can lead to critical hypoglycemia.
  • Moderate intraoperative glucose administration (2.5 mg/kg/min) is safe and does not cause significant hyperglycemia.