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Nociceptors and the peripheral nervous system's role in pain
1Department of Oral and Craniofacial Biological Sciences, University of Maryland, Baltimore, USA.
Abstract:
This article reviews the role that the peripheral nervous system plays in pain perception. The first section describes the functional properties of the primary sensory element-the nociceptor-and how its behavior is related to pain perception. The second section describes the current state of knowledge concerning the way our nociceptive sensing system changes as a result of tissue injury, including those changes related to sympathetic nervous system modulation of pain.