[Effect of immobilized noradrenaline on the contact phase of blood coagulation]

Specificity of interaction between factors of contact phase of blood coagulation and noradrenaline was studied. Human blood plasma lost the capacity to contact activation after chromatography on a column with noradrenaline-Sepharose. High specificity in binding of factors of contact phase with ligand-noradrenaline, "utilization" of factor XII during interaction with the ligand, the high specific activity of factor XII bound to noradrenaline-Sepharose were observed.