Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

SPECT scatter modelling in non-uniform attenuating objects

F J Beekman1, J M den Harder, M A Viergever

  • 1Image Sciences Institute, University Hospital Utrecht, The Netherlands. freek@cv.ruu.nl

Physics in Medicine and Biology
|June 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CT- DImQ: An open-access platform for image quality assessment of CT systems- application to CT values and noise characterization in 3D-printed anthropomorphic thorax phantoms.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2026
Same author

SPECT/CT imaging of inflammation and calcification in human carotid atherosclerosis to identify the plaque at risk of rupture.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology·2021
Same author

Corrigendum to "Effects of hunger state on the brain responses to food cues across the life span" [NeuroImage 171 (2018) 246-255].

NeuroImage·2021
Same author

The value of MRI STIR signal intensity on return to play prognosis and reinjury risk estimation in athletes with acute hamstring injuries.

Journal of science and medicine in sport·2021
Same author

Positron range-free and multi-isotope tomography of positron emitters.

Physics in medicine and biology·2021
Same author

The road to optimal acceleration of Dixon imaging and quantitative T2-mapping in the ankle using compressed sensing and parallel imaging.

European journal of radiology·2020
Same journal

Deep learning-based dose prediction to enhance planning efficiency in cervical brachytherapy with hybrid applicators.

Physics in medicine and biology·2026
Same journal

Corrigendum: Referenceless MR thermometry-a comparison of five methods (2017<i>Phys. Med. Biol</i>.<b>62</b>1-16).

Physics in medicine and biology·2026
Same journal

Corrigendum: Measured and Monte Carlo simulated electron backscatter to the monitor chamber for the varian TrueBeam linac (2016<i>Phys. Med. Biol</i>.<b>61</b>8779).

Physics in medicine and biology·2026
Same journal

Corrigendum: 3D range-modulator for scanned particle therapy: development, Monte Carlo simulations and experimental evaluation (2017<i>Phys. Med. Biol</i>.<b>62</b>7075).

Physics in medicine and biology·2026
Same journal

Recent progress in applications of computing to radiotherapy (ICCR 2016).

Physics in medicine and biology·2026
Same journal

Novel TMS coils designed using an inverse boundary element method.

Physics in medicine and biology·2026
See all related articles

Photon scatter degrades SPECT imaging. A new method, WEDECI, improves scatter modeling in non-uniform objects by considering only the

Area of Science:

  • Nuclear medicine
  • Medical imaging physics

Background:

  • Photon scatter significantly degrades quantitative accuracy and image contrast in Single Photon Emission Computed Tomography (SPECT).
  • Water Equivalent Depth (WED) methods have been employed to model scatter in non-uniform attenuators, but suffer from shape fluctuations in scatter response predictions.
  • Accurate scatter modeling is crucial for improving SPECT image quality and diagnostic reliability.

Purpose of the Study:

  • To present an improved method for modeling photon scatter in SPECT imaging.
  • To address the limitations of conventional Water Equivalent Depth (WED) methods in handling non-uniform attenuators.
  • To enhance the accuracy of scatter response predictions in SPECT.

Main Methods:

  • An enhanced Water Equivalent Depth method with Extra-Conical Invariance (WEDECI) was developed.

Related Experiment Videos

  • The WEDECI method assumes only the 'scatter cone' region significantly contributes to detected scatter events.
  • Projection measurements using a 99mTc source in a phantom were performed to evaluate the WEDECI method.

    • Main Results:

    • The WEDECI method demonstrated improved agreement between predicted and measured scatter response shapes compared to conventional WEDs.
    • The study successfully modeled scatter responses in a non-uniform attenuator phantom.
    • The enhanced WEDECI method reduces undesired fluctuations in scatter response modeling.

    Conclusions:

    • The WEDECI method offers a more accurate approach to modeling photon scatter in SPECT imaging.
    • This improvement is particularly beneficial for SPECT imaging involving non-uniform attenuating media.
    • WEDECI enhances SPECT quantitation and image contrast by providing better scatter correction.