[Management of Salmonella typhi and paratyphi carriers using Sulprim]

The sanation of carriers of Salmonella germs by means of bactericidal chemotherapy in combination with cholecystectomy is not to be expected in many patients with older age or when concomitant diseases are present. Therefore was tested, whether an exclusive therapy with trimethoprim-sulphamethoxazol (sulprim) is an effective method for the sanation of carriers of the salmonella germs with renunciation of cholecystectomy. Since 1973 up to now 20 carriers of germs have been treated for 12 weeks with daily 2 X 2 tablets of sulprim. Of these patients 84-year-old female patient died of massive pulmonary.