Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Macular hole surgery without face-down positioning. A pilot study

P E Tornambe1, L S Poliner, K Grote

  • 1Stanford Medical School, Palo Alto, California, USA.

Retina (Philadelphia, Pa.)
|January 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Is there a need in regulatory toxicity testing for evaluating chemicals at doses eliciting general toxicity?

Toxicology·2016
Same author

Postnatal investigation of prenatally induced effects on the vertebral column of rats reduces the uncertainty of classification of anomalies.

Reproductive toxicology (Elmsford, N.Y.)·2015
Same author

Toll-like receptor 2/6-dependent stimulation of mesenchymal stem cells promotes angiogenesis by paracrine factors.

European cells & materials·2013
Same author

Assessment strategies and decision criteria for pesticides with endocrine disrupting properties relevant to humans.

Reproductive toxicology (Elmsford, N.Y.)·2011
Same author

Histological alterations in ovaries of pubertal female rats induced by triphenyltin.

Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie·2008
Same author

In silico Northern blot, an automated method to determine expression patterns from EST databases, reveals tissue specificity of murine 17beta-hydroxysteroid dehydrogenase type 11.

Molecular and cellular endocrinology·2006
Same journal

Persistent placoid maculopathy: long term outcomes and prognostic factors.

Retina (Philadelphia, Pa.)·2026
Same journal

ANTI-VEGF THERAPY SWITCHING RETINAL DISEASES: Characterizing Clinical Manifestations and Common Involved Genes: ERRATUM.

Retina (Philadelphia, Pa.)·2026
Same journal

THE EFFICACY AND SAFETY OF SUBRETINAL BALANCED SALT SOLUTION INJECTION IN DIABETIC MACULAR EDEMA WITH HARD EXUDATES: ERRATUM.

Retina (Philadelphia, Pa.)·2026
Same journal

EVALUATING CLINICAL OUTCOMES OF AMNIOTIC MEMBRANE COVERAGE COMBINED WITH EARLY VITRECTOMY IN THE MANAGEMENT OF PERFORATING GLOBE INJURIES.

Retina (Philadelphia, Pa.)·2026
Same journal

Mid-Phase Hyperfluorescent Plaques as a biomarker of disease activity in Central Serous Chorioretinopathy: Clinical Course and Treatment Response - MICRoN report number Ten.

Retina (Philadelphia, Pa.)·2026
Same journal

Severe retinal non-perfusion is associated with fewer retinal lesions on ultra-wide field fundus photography in proliferative diabetic retinopathy.

Retina (Philadelphia, Pa.)·2026
See all related articles

Successful macular hole repair is achievable without face-down positioning. This approach offers a viable alternative for patients unable to maintain prone posturing, improving surgical eligibility.

Area of Science:

  • Ophthalmology
  • Retinal Surgery
  • Macular Degeneration Research

Background:

  • Face-down positioning is a common but unproven method for macular hole closure.
  • Prone posturing presents significant challenges for patients with physical or cognitive limitations.
  • Complete vitreous gas fill may effectively tamponade macular holes regardless of head position.

Purpose of the Study:

  • To determine if face-down positioning is essential for successful macular hole repair.
  • To evaluate an alternative surgical technique for macular hole closure.

Main Methods:

  • 33 patients (65-79 years) with Stage II-IV macular holes received surgery with a complete 15% C3F8 vitreous fill.
  • No patients underwent postoperative face-down positioning.

Related Experiment Videos

  • Phakic patients (n=25) also underwent cataract extraction and intraocular lens insertion.
  • Main Results:

    • The overall success rate for macular hole closure was 85% (28/33 eyes) after one or more surgeries.
    • 48% of eyes achieved a visual acuity of 20/50 or better.
    • Preoperative hole duration did not impact closure rates.

    Conclusions:

    • Macular hole closure can be successful without face-down positioning.
    • This technique is a potential alternative for pseudophakic and phakic patients unable to maintain prone positioning.
    • Combining cataract surgery with macular hole repair is feasible for select patients.