Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mesiodentes: incidence, morphology, etiology

A Stellzig1, E K Basdra, G Komposch

  • 1Poliklinik für Kieferorthopädie, Klinik für Mund-, Zahn- und Kieferkrankheiten, Universität Heidelberg.

Journal of Orofacial Orthopedics = Fortschritte Der Kieferorthopadie : Organ/Official Journal Deutsche Gesellschaft Fur Kieferorthopadie
|January 1, 1997
PubMed
Summary

Inheritance plays a key role in the development of mesiodentes, a common supernumerary tooth. This study also suggests genetic links between mesiodentes and other dental anomalies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Role of Cathepsin S in Periodontal Inflammation and Infection.

Mediators of inflammation·2018
Same author

Flavonoids in atherosclerosis: an overview of their mechanisms of action.

Current medicinal chemistry·2013
Same author

Elevation of collagen type I in fibroblast-keratinocyte cocultures emphasizes the decisive role of fibroblasts in the manifestation of the phenotype of cyclosporin A-induced gingival overgrowth.

Journal of periodontal research·2008
Same author

[Predictors for compliance in orthodontic treatment].

Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))·2008
Same author

[Different patterns of velopharyngeal dysfunction in cleft palate patients].

HNO·2007
Same author

The MAPK-AP-1/-Runx2 signalling axes are implicated in chondrosarcoma pathobiology either independently or via up-regulation of VEGF.

Histopathology·2005

Area of Science:

  • Dentistry
  • Genetics
  • Developmental Biology

Background:

  • Mesiodentes are supernumerary teeth located in the anterior maxilla.
  • Etiology of mesiodentes is not well understood, despite extensive research on clinical aspects.
  • Previous studies have focused on treatment rather than causes.

Purpose of the Study:

  • To investigate the etiologic factors contributing to mesiodentes development.
  • To evaluate the role of inheritance and potential links to other dental anomalies.
  • To explore theories regarding tooth bud development in relation to mesiodentes.

Main Methods:

  • Retrospective analysis of 30 patients with 45 mesiodentes.
  • Assessment of familial disposition and inheritance patterns.

Related Experiment Videos

  • Comparison of dental anomalies and tooth morphology.
  • Main Results:

    • A familial disposition was observed in 31% of patients, indicating a significant role for inheritance.
    • Findings support a link between mesiodentes and other anomalies like hyperdontia, hypodontia, and cleft lip/palate.
    • Gemination of a deciduous incisor and altered central incisor width were noted, supporting the dichotomy theory.

    Conclusions:

    • Inheritance is a significant etiologic factor for mesiodentes.
    • Mesiodentes may share common etiologic pathways with other dental and craniofacial anomalies.
    • The dichotomy theory, involving tooth bud splitting, is favored over dental lamina hyperactivity for mesiodentes development.