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Biological effects of the immunomodulator beta 1-3D polyglucose are strongly potentiated by conjugation to
1Institute of Medical Biology, University of Tromsø, Norway.
Scandinavian Journal of Immunology
|June 1, 1997
Abstract:
It is demonstrated that the biological effects of the immunomodulator beta 1-3D polyglucose, when covalently linked to polymethacrylate or biodegradable albumin microbeads, are strongly potentiated. The potentiation is recorded as an increased protection effect of the conjugates in Escherichia coli sepsis in mice, and as increased IL-1 production by murine macrophages in vitro.