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[Acute schistosomiasis with brain involvement. Case report]

C D Urban1, E J Piovesan, S M De Almeida

  • 1Departamento de Clínica Médica, Hospital de Clínicas da Universidade, Federal do Paraná (UFPR), Curitiba, Brasil.

Arquivos De Neuro-Psiquiatria
|December 1, 1996
PubMed
Summary
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Acute schistosomiasis can affect the brain, presenting as demyelinating lesions on MRI. Antibody detection confirmed the diagnosis, and treatment with praziquantel and prednisolone was effective.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Immunology

Background:

  • Schistosomiasis is a parasitic disease typically affecting the spinal cord.
  • Cerebral involvement by Schistosoma mansoni is infrequently reported but may be underestimated.

Observation:

  • A case of acute schistosomiasis with neurological symptoms including pyramidal disorder.
  • Magnetic resonance imaging (MRI) revealed brain lesions suggestive of demyelination.
  • Cerebrospinal fluid analysis was normal, complicating initial diagnosis.

Findings:

  • Diagnosis was confirmed by detecting Schistosoma mansoni antibodies in blood and cerebrospinal fluid.
  • The patient responded well to treatment with praziquantel and prednisolone.

Implications:

Related Experiment Videos

  • This case highlights the potential for cerebral demyelination in acute schistosomiasis.
  • Further research is needed to clarify the pathophysiology and optimal treatment for neuroschistosomiasis.
  • Increased awareness and diagnostic vigilance for brain involvement in schistosomiasis are warranted.