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Trazodone for aggression in an adolescent with hydrocephalus
H Mashiko1, H Yokoyama, H Matsumoto
1Department of Neuropsychiatry, Fukushima Medical College, Japan.
Psychiatry and Clinical Neurosciences
|June 1, 1996
Summary
Trazodone effectively treated aggressive self-injurious behaviors in a 19-year-old male with hydrocephalus, even when conventional treatments failed. This case highlights trazodone
Area of Science:
- Neuroscience and Psychiatry
- Pharmacology
Background:
- Aggressive self-injurious behaviors (SIB) present a significant challenge in patients with neurological conditions.
- Conventional pharmacotherapy and psychotherapy often prove ineffective for severe SIB in adolescents.
- Hydrocephalus can be associated with behavioral disturbances, including aggression and self-harm.
Observation:
- A 19-year-old male with hydrocephalus exhibited severe self-injurious behaviors, withdrawal, and eating refusal.
- Previous treatments including antidepressants, antipsychotics, anxiolytics, anticonvulsants, psychotherapy, and electroconvulsive therapy were ineffective for 15 months.
Findings:
- Trazodone administration for 5 months led to significant improvement in the patient's aggressive behaviors.
- This case is notable as adolescent cases responding to trazodone for organic brain syndrome-related aggression are rare.
Implications:
- Trazodone may be a viable treatment option for aggressive self-injurious behaviors in adolescents with hydrocephalus.
- Further research is warranted to explore trazodone's efficacy in younger populations with similar conditions.