Bradycardia following intravenous ketorolac in children

P N Foster1, J G Williams

  • 1Royal Preston Hospital, Fulwood, Preston, UK.

Insights

Intravenous ketorolac administration in children may cause bradycardia, a slow heart rate. This report details two cases and offers guidance on ketorolac use during surgery.

Area of Science:

  • Pediatric Anesthesiology
  • Pharmacology

Background:

  • Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for pain management.
  • Intravenous administration is utilized for rapid and effective analgesia in surgical settings.

Observation:

  • Two pediatric patients developed bradycardia during intraoperative procedures.
  • Bradycardia occurred shortly after the intravenous administration of ketorolac.

Findings:

  • The observed bradycardia suggests a potential adverse effect of intravenous ketorolac in pediatric patients.
  • The mechanism linking ketorolac to bradycardia in this population warrants further investigation.

Implications:

  • Clinicians should be vigilant for bradycardia when administering intravenous ketorolac to children.
  • Recommendations for the safe intraoperative use of ketorolac in pediatric anesthesia are proposed.

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