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Bradycardia following intravenous ketorolac in children
1Royal Preston Hospital, Fulwood, Preston, UK.
Insights
Intravenous ketorolac administration in children may cause bradycardia, a slow heart rate. This report details two cases and offers guidance on ketorolac use during surgery.
Area of Science:
- Pediatric Anesthesiology
- Pharmacology
Background:
- Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for pain management.
- Intravenous administration is utilized for rapid and effective analgesia in surgical settings.
Observation:
- Two pediatric patients developed bradycardia during intraoperative procedures.
- Bradycardia occurred shortly after the intravenous administration of ketorolac.
Findings:
- The observed bradycardia suggests a potential adverse effect of intravenous ketorolac in pediatric patients.
- The mechanism linking ketorolac to bradycardia in this population warrants further investigation.
Implications:
- Clinicians should be vigilant for bradycardia when administering intravenous ketorolac to children.
- Recommendations for the safe intraoperative use of ketorolac in pediatric anesthesia are proposed.
Abstract:
Two cases of bradycardia following the intra-operative use of ketorolac given intravenously (i.v.) to children are reported. We examine why this may not have been previously reported and make recommendations regarding its use.
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