Jove
Visualize
Contact Us

Related Experiment Videos

Postnatal steroid therapy in neonates

T E Young1

  • 1Division of Neonatology, Wake Area Health Education Center, Raleigh, NC 27620-4465, USA.

Current Opinion in Pediatrics
|April 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Establishing the European Norm for the health-related quality of life domains of the computer-adaptive test EORTC CAT Core.

European journal of cancer (Oxford, England : 1990)·2018
Same author

General population normative data for the EORTC QLQ-C30 health-related quality of life questionnaire based on 15,386 persons across 13 European countries, Canada and the Unites States.

European journal of cancer (Oxford, England : 1990)·2018
Same author

The Queen's Hospital for Children.

The Hospital·2018
Same author

The international phase 4 validation study of the EORTC QLQ-SWB32: A stand-alone measure of spiritual well-being for people receiving palliative care for cancer.

European journal of cancer care·2017
Same author

An in vitro method for screening for the presence of thepat-2 gene in tomatoes (Lycopersicon esculentum Mill.).

Plant cell reports·2013
Same author

Identification and bioassay of kairomones forHelicoverpa zea.

Journal of chemical ecology·2013
Same journal

For health, for beauty, or both? navigating trends as adolescent clinicians.

Current opinion in pediatrics·2026
Same journal

Childhood sleep disorders: practical management for the pediatrician.

Current opinion in pediatrics·2026
Same journal

Advanced therapies in management of pediatric inflammatory bowel disease.

Current opinion in pediatrics·2026
Same journal

Artificial intelligence in pediatric endoscopy for hereditary polyposis syndromes: promises and challenges.

Current opinion in pediatrics·2026
Same journal

Hormonal acne therapies in pediatrics.

Current opinion in pediatrics·2026
Same journal

Clinical implementation of artificial intelligence in adolescent mental healthcare.

Current opinion in pediatrics·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Dexamethasone use in neonates for mechanical ventilation weaning is common but lacks proven long-term benefits. Early intervention and risk assessment may improve outcomes, but further research is needed.

Area of Science:

  • Neonatal Medicine
  • Pediatric Pulmonology
  • Pharmacology

Background:

  • Dexamethasone is frequently used to aid neonatal weaning from mechanical ventilation.
  • Current evidence shows limited improvement in long-term pulmonary and neurodevelopmental outcomes despite widespread use.
  • Significant controversy exists regarding optimal treatment protocols and minimizing adverse effects.

Purpose of the Study:

  • To evaluate the effectiveness of dexamethasone in neonatal mechanical ventilation weaning.
  • To explore strategies for improving patient selection and treatment outcomes.
  • To address the controversies surrounding dexamethasone use in neonates.

Main Methods:

  • Review of existing studies on dexamethasone for neonatal mechanical ventilation.

Related Experiment Videos

  • Analysis of factors influencing treatment outcomes, including timing and dosage.
  • Exploration of risk assessment tools for patient selection.

    • Main Results:

    • Most studies do not demonstrate significant long-term pulmonary or neurodevelopmental benefits.
    • Early treatment before significant inflammation may offer improved outcomes and shorter courses.
    • Risk assessment tools could enhance patient selection.

    Conclusions:

    • The efficacy and optimal use of dexamethasone for neonatal mechanical ventilation weaning remain debated.
    • Further large-scale, long-term studies are necessary to clarify benefits and risks.
    • Refined patient selection and early intervention strategies warrant investigation.