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Prediction of N-terminal protein sorting signals
M G Claros1, S Brunak, G von Heijne
1Laboratorio de Bioqumica y Biologa Molecular, Facultad de Ciencias, Universidad de Málaga, Spain.
Current Opinion in Structural Biology
|June 1, 1997
Abstract:
Recently, neural networks have been applied to a widening range of problems in molecular biology. An area particularly suited to neural-network methods is the identification of protein sorting signals and the prediction of their cleavage sites, as these functional units are encoded by local, linear sequences of amino acids rather than global 3D structures.