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[Computed tomographic features of malignant fibrous histiocytoma]
1Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing.
Abstract:
CT findings in 45 cases of malignant fibrous histiocytoma (MFH) were reviewed. There were 27 primary and 22 (23 episodes) cases of recurrent tumor, 4 (5 episodes) cases of recurrent tumor were initially treated in our hospital. Tumors located in craniofacial area in 16 cases, abdomen or retroperitoneum in 17, soft tissues of extremities or trunk in 12. There were 26 male and 19 female patients, with 19-82 years of age (medium, 46 years of age). The most common clinical symptom was a local mass (64.4%). On CT scan, 84% (42/50) of lesions with tumor mass > 5 cm, mostly with irregular contour, medium to markedly hyper-attenuated enhancement were revealed in 78.8% of cases and 60.6% of cases with hypo-attenuated necrotic area inside. Most of the tumors invaded adjacent organs or structures which were revealed in 75.8% of cases, such as infratemporal fossa, pterygopalatine fossa, extradural space in the craniofacial lesions; liver, psoas muscle, abdominal wall in abdominal and retroperitoneal lesions. Expansible change could be shown when paranasal sinus was invaded (8/9). The CT findings of recurrent lesions were similar to the primary ones. Enhanced CT scan may provide useful information in demonstrating the nature and extent of invasion of the tumor. Closely integrating CT and pathologic findings is important for the differential diagnosis of malignant tumors of soft tissue.