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Mitomycin-C supplemented trabeculectomy, phacoemulsification, and foldable lens implantation
K J Yang1, M R Moster, A Azuara-Blanco
1Glaucoma Service, Wills Eye Hospital, Jefferson Medical College, Philadelphia, Pennsylvania 19107, USA.
Journal of Cataract and Refractive Surgery
|May 1, 1997
Summary
Combined mitomycin-C filtering surgery with phacoemulsification and intraocular lens (IOL) implantation offers high success rates for glaucoma patients. This procedure effectively controls intraocular pressure (IOP) and improves visual acuity with a low complication rate.
Area of Science:
- Ophthalmology
- Glaucoma Surgery
- Cataract Surgery
Background:
- Glaucoma management often requires surgical intervention to control intraocular pressure (IOP).
- Combined procedures aim to address both glaucoma and cataract simultaneously, potentially improving efficiency and outcomes.
Purpose of the Study:
- To evaluate the efficacy and safety of combined mitomycin-C trabeculectomy, phacoemulsification, and foldable intraocular lens (IOL) implantation.
- To assess the long-term intraocular pressure control and visual acuity outcomes of this combined surgical approach.
Main Methods:
- Retrospective study of 182 eyes from 174 patients undergoing the combined procedure.
- Success defined as IOP < 21 mm Hg with or without medication and no serious complications.
- Kaplan-Meier method used for calculating success rates.
Main Results:
- High probability of success at 24 months (88.0%).
- Significant improvement in visual acuity, with 81.3% of eyes gaining one or more lines.
- Posterior capsule opacification (12.0%) was the most common complication.
Conclusions:
- Combined mitomycin-C filtering surgery, phacoemulsification, and IOL implantation demonstrate high IOP control rates at 1 and 2 years.
- The procedure is effective in managing glaucoma and cataracts concurrently.
- Visual acuity improvements and acceptable complication rates support its use.