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Apoptosis to HL-60 by humulone
H Tobe1, M Kubota, M Yamaguchi
1Showa College of Pharmaceutical Sciences, Tokyo, Japan.
Bioscience, Biotechnology, and Biochemistry
|June 1, 1997
Abstract:
Humulone, a bone resorption inhibitor isolated from hop extract, induced apoptosis in the premyocytic leukemia cell line HL-60 between 1 and 100 micrograms/ml. Our data suggested that there was a correlation between the apoptosis-inducing activity of humulone and its antioxidative activity.