Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

1.2K
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
1.2K
Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

1.8K
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
1.8K
External and Internal Respiration01:24

External and Internal Respiration

8.1K
External respiration occurs in the lungs, and it is the first step in the journey of oxygen inside the body. When we inhale, oxygen enters our lungs and diffuses across the thin alveolar membrane. The alveoli are tiny, air-filled sacs that provide a vast surface area for gas exchange. Oxygen in the alveoli has a higher partial pressure (105 mmHg) than in the adjacent pulmonary capillaries (40 mmHg), establishing a pressure gradient. As a result, oxygen molecules move from the alveoli into the...
8.1K
Lung Capacity01:47

Lung Capacity

56.5K
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
56.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Near-infrared spectroscopy assessed cerebral oxygenation during open abdominal aortic aneurysm repair: relation to end-tidal CO2 tension.

Journal of clinical monitoring and computing·2015
Same author

Hypoxia increases exercise heart rate despite combined inhibition of β-adrenergic and muscarinic receptors.

American journal of physiology. Heart and circulatory physiology·2015
Same author

Release of erythropoietin and neuron-specific enolase after breath holding in competing free divers.

Scandinavian journal of medicine & science in sports·2014
Same author

Aerobic exercise capacity at long-term follow-up after paediatric allogeneic haematopoietic SCT.

Bone marrow transplantation·2014
Same author

Cardiac output during exercise: a comparison of four methods.

Scandinavian journal of medicine & science in sports·2014
Same author

External carotid artery flow maintains near infrared spectroscopy-determined frontal lobe oxygenation during ephedrine administration.

British journal of anaesthesia·2014

Related Experiment Video

Updated: Feb 20, 2026

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise
09:33

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise

Published on: December 19, 2024

1.6K

Restricted postexercise pulmonary diffusion capacity and central blood volume depletion

B Hanel1, I Teunissen, A Rabol

  • 1Department of Clinical Physiology, Copenhagen Muscle Research Center, Rigshospitalet, DK-2100 Copenhagen, Denmark.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|July 1, 1997
PubMed
Summary

Intense rowing exercise reduces pulmonary diffusion capacity for carbon monoxide (DLCO) by decreasing pulmonary blood volume. Lower plasma atrial natriuretic peptide (ANP) levels after exercise indicate a role in blood volume regulation.

More Related Videos

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
08:44

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

1.4K
Assessment of Pulmonary Capillary Blood Volume, Membrane Diffusing Capacity, and Intrapulmonary Arteriovenous Anastomoses During Exercise
07:09

Assessment of Pulmonary Capillary Blood Volume, Membrane Diffusing Capacity, and Intrapulmonary Arteriovenous Anastomoses During Exercise

Published on: February 20, 2017

13.8K

Related Experiment Videos

Last Updated: Feb 20, 2026

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise
09:33

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise

Published on: December 19, 2024

1.6K
Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
08:44

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

1.4K
Assessment of Pulmonary Capillary Blood Volume, Membrane Diffusing Capacity, and Intrapulmonary Arteriovenous Anastomoses During Exercise
07:09

Assessment of Pulmonary Capillary Blood Volume, Membrane Diffusing Capacity, and Intrapulmonary Arteriovenous Anastomoses During Exercise

Published on: February 20, 2017

13.8K

Area of Science:

  • Exercise Physiology
  • Cardiopulmonary Function
  • Biomedical Engineering

Background:

  • Pulmonary diffusion capacity for carbon monoxide (DLCO) is a key measure of lung function.
  • Exercise can alter blood volume distribution and impact DLCO.
  • Atrial natriuretic peptide (ANP) plays a role in fluid balance.

Purpose of the Study:

  • To investigate the effects of intense rowing exercise on DLCO, blood volume distribution, and plasma ANP levels.
  • To determine the relationship between changes in pulmonary blood volume and DLCO post-exercise.
  • To explore the role of ANP in post-exercise cardiovascular regulation.

Main Methods:

  • Measurements of DLCO, regional electrical impedance (Z0), and technetium-99m-labeled erythrocyte distribution before and after a 6-minute "all-out" row.
  • Assessment of plasma ANP concentration in nine oarsmen and six control subjects.
  • Comparison of responses in upright seated and supine positions.

Main Results:

  • Post-exercise, DLCO decreased significantly in oarsmen (6-12%), accompanied by an increased thoracic-to-thigh electrical impedance ratio (10-14%).
  • This impedance change indicated a redistribution of blood volume, with decreased thoracic and increased thigh volumes.
  • Plasma ANP concentration decreased post-exercise (P < 0.05), correlating with reduced pulmonary blood volume and DLCO.
  • DLCO remained stable in the control group, highlighting exercise-induced effects.

Conclusions:

  • Approximately 50% of the post-exercise reduction in DLCO is attributable to a decrease in pulmonary blood volume.
  • Reduced central blood volume post-exercise, evidenced by lower ANP levels, is a significant factor.
  • ANP may play a role in the upregulation of blood volume following strenuous exercise in athletes.