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[Laxative policy for terminal patients ineffective]

J Schoorl1, Z Zylicz

  • 1Rijksuniversiteit Limburg, Faculteit der Geneeskunde, Maastricht.

Nederlands Tijdschrift Voor Geneeskunde
|April 26, 1997
PubMed
Summary

Constipation is common in terminal patients, especially those using opioids. Current laxative policies, including fixed lactulose doses, are ineffective for managing constipation in this population.

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Area of Science:

  • Palliative Care
  • Gastroenterology
  • Pharmacology

Context:

  • Retrospective study conducted at Hospice Rozenheuvel in the Netherlands.
  • Analyzed data from 121 patients admitted for terminal care between January 1995 and July 1996.
  • Focus on constipation prevalence and laxative use in terminally ill patients.

Purpose:

  • To determine the prevalence of constipation in terminally ill patients.
  • To assess the effectiveness of current laxative policies in this patient group.
  • To evaluate the impact of opioid use on constipation and laxative efficacy.

Summary:

  • 48% of patients were constipated upon admission; 51% used opioids.
  • Opioid users experienced constipation more frequently (68% vs. 27%).
  • Laxatives, including fixed-dose lactulose, were ineffective in managing constipation in both opioid users and non-users.

Impact:

  • Highlights the ineffectiveness of current laxative management strategies in terminal care.
  • Suggests a need for revised approaches to constipation management in palliative care.
  • Underscores the challenges in treating opioid-induced constipation in end-of-life care.

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