[Hyperbaric oxygenation and antiaggregants: effects on platelet function in patients with ischemic heart disease]

Platelet function (duration and percentage of aggregation and disaggregation) was studied in 65 chronic coronary patients over the course of hyperbaric oxygenation and antiaggregant therapy. A course of hyperbaric oxygenation (8 to 12 sessions at absolute atmosphere of 1.3-1.6 for 40 min) had no proaggregant or antiaggregant effects on the platelets in this category of patients. Aspirin in a daily dose of 125 mg and pentoxifylline in a daily dose of 300 mg reliably decreased the percentage of platelet aggregation and increased the share of disaggregation. Hyperbaric oxygenation in the above mode did not change the antiaggregant activity of these drugs.