Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Memory impairment in multiple sclerosis: a quantitative review

A E Thornton1, N Raz

  • 1Department of Psychology, University of Memphis, USA. althornton@aol.com

Neuropsychology
|July 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A (Sub)field Guide to Quality Control in Hippocampal Subfield Segmentation on Highresolution T<sub>2</sub>-weighted MRI.

bioRxiv : the preprint server for biology·2023
Same author

Prenatal diagnosis of rhombencephalosynapsis: neuroimaging features and severity of vermian anomaly.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2021
Same author

Hippocampal volume and vasculature before and after exercise in treatment-resistant schizophrenia.

Schizophrenia research·2018
Same author

Jugular Anomalies in Multiple Sclerosis Are Associated with Increased Collateral Venous Flow.

AJNR. American journal of neuroradiology·2017
Same author

Electrophysiological and psychophysical correlates of spatial summation to noxious heat: the possible role of A-delta fibers.

Experimental brain research·2016
Same author

Visual working memory deterioration preceding relapse in psychosis.

Psychological medicine·2016
Same journal

The association between daily real-time assessment of subjective cognitive function and objective cognition using ecological momentary assessment.

Neuropsychology·2026
Same journal

Obtaining comparable measurement of midlife cognitive functioning from disparate cognitive tasks.

Neuropsychology·2026
Same journal

Cognitive impairments associated with meningiomas and gliomas in adults: A systematic review.

Neuropsychology·2026
Same journal

Neuropsychological assessment in low-resource versus high-resource contexts: A reply to comments on Stiers (2026).

Neuropsychology·2026
Same journal

Testing is important: A truism worth remembering.

Neuropsychology·2026
Same journal

Of dogs and diagnoses: Does clinical reasoning still matter in an age of biomarkers, functional imaging, and artificial intelligence?

Neuropsychology·2026
See all related articles

Multiple sclerosis (MS) significantly impairs memory across short-term, working, and long-term domains. These memory deficits are linked to neurological disability and disease progression in MS patients.

Area of Science:

  • Neuroscience
  • Cognitive Psychology

Background:

  • Multiple sclerosis (MS) is a chronic neurological disease.
  • Cognitive impairments, particularly memory deficits, are common in MS.
  • The precise pattern and extent of memory impairment in MS require further elucidation.

Purpose of the Study:

  • To quantitatively assess the nature and magnitude of memory impairment in MS.
  • To examine memory performance across short-term memory (STM), working memory (WM), and long-term memory (LTM).
  • To investigate the influence of retrieval support, WM-LTM covariation, and clinical MS characteristics on memory deficits.

Main Methods:

  • Meta-analysis of 36 studies comparing memory performance in MS patients versus healthy controls.
  • Quantitative analysis of memory impairment patterns across different memory domains (STM, WM, LTM).

Related Experiment Videos

  • Exploration of moderating factors including retrieval support and clinical MS features.

    • Main Results:

    • Significant memory impairment was observed across all memory domains (STM, WM, LTM) in individuals with MS.
    • Evidence did not support a retrieval-based explanation for long-term memory dysfunction in MS.
    • Strong associations were identified between the severity of memory impairment and clinical characteristics of MS, such as neurological disability and disease course.

    Conclusions:

    • MS is associated with a more global pattern of memory deficits than previously recognized.
    • Memory impairments in MS are significantly linked to the individual's neurological disability and the disease's progression.
    • These findings underscore the widespread cognitive impact of MS on memory functions.