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Monoclonal gammopathy in a Dutch warmblood mare
S N Geelen1, W E Bernadina, G C Grinwis
1Department of Large Animal Medicine and Nutrition, Utrecht University, Faculty of Veterinary Medicine, The Netherlands.
The Veterinary Quarterly
|March 1, 1997
Abstract:
A 15-year-old Dutch warmblood mare was presented because of lethargy, which had been present for several weeks, and severe anaemia. Total protein was high and serum electrophoresis revealed a monoclonal peak in the alpha-2 region. Monoclonal immunoglobulin, IgG(T), was detected by immuno-electrophoresis in serum and urine. Postmortem examination revealed a relatively large number of plasmacytoid cells in the bone marrow and a monotonous population of plasmacytoid cells in the spleen. These findings are suggestive of a plasma cell myeloma.