[Fractional plasmapheresis in therapeutic experience: methodological approach]

The aim of the study was estimation of the incidence rate of complications arising in the course of fractional plasmapheresis (FPA), the analysis of their causes and design of prophylactic measures. 139 courses comprising 410 FPA sessions were delivered in 118 patients with various diseases. The highest rate of complications was 4.7%. If put on FPA without previous preparation, the patient experienced marked hypotension because of fast escape from circulation of 500 ml of blood. Induction of short-term hypervolemia in patients with low arterial pressure prevents emergence of cardiovascular complications in the course of blood exfusion.