[Severe streptococcal complications in varicella]

M C Héraud1, Y Loriette, A Grassano

  • 1Unité de réanimation et des maladies respiratoires, CHRU de Clermont-Ferrand, Hôtel-Dieu, France.

Insights

Group A beta-hemolytic streptococcal (GABHS) infections are increasingly seen with varicella in children. Early recognition of GABHS complications like septic shock and cellulitis in febrile children with varicella is crucial.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Microbiology

Background:

  • Recent reports indicate a rise in group A beta-hemolytic streptococcal (GABHS) infections among children.
  • A frequent association between GABHS infections and varicella (chickenpox) has been observed.

Observation:

  • Two pediatric cases illustrate severe GABHS complications following varicella.
  • Case 1: A 3-year-old developed septic shock and osteomyelitis due to GABHS after varicella.
  • Case 2: A 4.5-year-old presented with cellulitis and adenitis, with both Staphylococcus aureus and GABHS identified.

Findings:

  • GABHS infections can manifest as severe conditions like septic shock, osteomyelitis, and cellulitis in children with varicella.
  • Early and appropriate antibiotic therapy is essential for managing these invasive streptococcal infections.
  • Varicella can serve as a portal for secondary bacterial infections, particularly GABHS.

Implications:

  • Clinicians should maintain a high index of suspicion for GABHS infections in children with varicella who present with persistent fever or unusual symptoms.
  • Increased vigilance for GABHS complications is necessary in pediatric varicella cases.
  • Prompt diagnosis and management of GABHS infections associated with varicella can improve patient outcomes and prevent severe sequelae.
Abstract

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