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[Struma ovarii or malignant ovarian goiter. A case]
G Barrande1, C Munz, B de Rochambeau
1Service d'Endocrinologie et Métabolisme, Hôpital Saint-Joseph, Paris.
Presse Medicale (Paris, France : 1983)
|June 7, 1997
Summary
This case report details a rare follicular struma ovarii within an ovarian teratoma. The patient received successful treatment with ovariectomy and radioactive iodine therapy.
Area of Science:
- Gynecologic Oncology
- Endocrinology
- Pathology
Background:
- Struma ovarii is a rare germ cell tumor originating from ectopic thyroid tissue within an ovarian teratoma.
- Malignant transformation of struma ovarii is exceptionally rare, accounting for less than 1% of cases.
Observation:
- A 31-year-old woman presented with lower abdominal pain due to a 4-cm right ovarian cystic mass.
- Laparoscopic removal revealed a follicular type malignant struma ovarii with teratomatous elements and vascular invasion.
Findings:
- Immunohistochemical staining confirmed the thyroidal origin of the tumor.
- The patient underwent successful treatment including right ovariectomy, total thyroidectomy, and radioactive iodine (I-131) therapy.
- A 6-month follow-up I-131 body scan showed no evidence of residual or metastatic disease.
Implications:
- This case highlights the importance of thorough pathological examination for diagnosing malignant struma ovarii.
- Definitive treatment involves surgical resection and potentially radioactive iodine ablation for malignant cases.
- Establishing clear diagnostic criteria for malignancy remains crucial for appropriate patient management.