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Antiviral activity of cyclopentenone prostanoids
1Institute of Experimental Medicine, CNR, Rome, Italy. santoro@biocell.irmkant.rm.cnr.it
Trends in Microbiology
|July 1, 1997
Abstract:
Cyclopentenone prostanoids inhibit virus replication by turning on an intracellular defence response that involves the induction of cytoprotective heat-shock proteins, the modification of viral glycoprotein maturation and the control of NF-kappa B activation. These molecules represent an interesting model for the development of novel antiviral drugs that can affect different targets during the virus life cycle.