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[Epidemiological evaluations of the incidence of posttransfusion hepatitis in Iaşi County in 1985-1995]
A Ivan1, D Azoicăi, R Grigorescu
1U.M.F. Gr. T. Popa, Iaşi.
Abstract:
In the interval 1985-1995 the morbidity rate of viral hepatitis of various causes showed yearly variations, an average of 181 cases being recorded. The performed investigations revealed markers for viral hepatitis B in an yearly average of 154 cases for the 11 years under study. Posttransfusion hepatitis had an average incidence of 43 cases per year, in 59.1% the markers for viral hepatitis B being absent. 93.3% of the cases with posttransfusion hepatitis belonged to the age groups over 20 years and workers presented a mean yearly incidence of 28.3% of all cases. In 1995 the blood donors with viral hepatitis C antibodies represented 4.05% and 75% of them belonged to the age groups 21-60 years, 50% of them being industrial workers and 40% having the A II blood group. Of the 321 admitted cases, 26.7% presented AgHBs, 8.4% AcVHC, in 2.3% markers for both viruses were evidenced and in 62.8% of the cases the diagnosis was made on epidemiological criteria and serologic exclusion (non A, B, C) without excluding the possible intervention of other hepatitic viruses.
Insights
Viral hepatitis morbidity varied between 1985-1995. Viral hepatitis B was common, while post-transfusion hepatitis often lacked B markers and affected adults and workers.
Area of Science:
- Hepatology
- Virology
- Epidemiology
Context:
- Viral hepatitis represents a significant public health concern with varying etiological factors.
- Understanding the epidemiology of viral hepatitis is crucial for effective prevention and control strategies.
- The period 1985-1995 witnessed significant shifts in the understanding and diagnosis of viral hepatitis.
Purpose:
- To analyze the morbidity rates and etiological characteristics of viral hepatitis.
- To investigate the prevalence of viral hepatitis B and C markers in specific populations.
- To identify risk factors and demographic associations for post-transfusion hepatitis.
Summary:
- Viral hepatitis morbidity averaged 181 cases annually between 1985-1995, with Hepatitis B markers found in 154 cases.
- Post-transfusion hepatitis occurred in 43 cases/year, often lacking Hepatitis B markers (59.1%), predominantly in adults over 20 and workers.
- In 1995, 4.05% of blood donors had Hepatitis C antibodies, with a concentration in the 21-60 age group, industrial workers, and blood group A II.
Impact:
- Highlights the changing landscape of viral hepatitis, emphasizing the need to consider non-B Hepatitis B causes in post-transfusion cases.
- Provides epidemiological data on viral hepatitis B and C, informing blood screening and public health interventions.
- Underscores the importance of serological and epidemiological criteria for diagnosing viral hepatitis, especially in cases without identifiable markers.
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