Dermatologic drugs, pregnancy, and lactation. A conservative guide

Area of Science:

• Dermatology
• Pharmacology
• Teratology

Background:

• No comprehensive database exists for precise risk assessment of drug use during pregnancy and lactation.
• Expert opinions from manufacturers, regulatory bodies, and health organizations guide drug use decisions.
• Some medications can be used safely during pregnancy and lactation without adverse effects.

Purpose of the Study:

• To summarize dermatologic drugs with a known low risk profile for use in pregnant and lactating individuals.
• To provide guidance for selecting medications with minimal risk during the childbearing years.

Main Methods:

• Literature review and synthesis of expert opinions and available data on dermatologic drug safety.
• Focus on drugs with extensive use and documented lack of apparent adverse effects in mothers or infants.

Main Results:

• Identified several dermatologic medications with a low known risk for use during pregnancy and lactation.
• Highlighted that not all drugs are contraindicated, and some have a history of safe application.

Conclusions:

• When medication is necessary during pregnancy or lactation, selection should prioritize drugs with minimal known risk.
• This summary aids clinicians in making informed decisions regarding dermatologic treatments for vulnerable populations.