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Neurovascular [125I]-ET-1 binding sites on human peripheral nerve

M R Dashwood1, P K Thomas

  • 1Department of Physiology, Royal Free Hospital School of Medicine, London, UK.

Endothelium : Journal of Endothelial Cell Research
|January 1, 1997
PubMed

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Cholinergic Receptors: Nicotinic01:15

Cholinergic Receptors: Nicotinic

Nicotinic receptors are ligand-gated ion channels that are activated by acetylcholine and nicotine. Upon activation, they cause a rapid increase in the permeability of cells to K+, Na+, and Ca2+, followed by depolarization and excitation. They are in the autonomic ganglia, skeletal neuromuscular junction, CNS, and adrenal medulla.
There are two types of nicotinic receptors: neuromuscular (NM/NM/N1) and neuronal (NN/NN/N2). The two families differ based on their location and selectivity to...