Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The relationship between the immune and endocrine systems

A Chryssikopoulos1

  • 1Second Department of Obstetrics and Gynecology, University of Athens, Areteion Hospital, Greece.

Annals of the New York Academy of Sciences
|June 17, 1997
PubMed
Summary

The immune and endocrine systems are interconnected. Hormones and cytokines influence each other

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Non classical congenital adrenal hyperplasia due to 21-hydroxylase deficiency in families from a Greek island with a closed society.

Clinical and experimental obstetrics & gynecology·2009
Same author

Hypothalamic-pituitary-thyroidal axis dysfunction and cortisol secretion in patients with nonclassical congenital adrenal hyperplasia.

International journal of fertility and women's medicine·2001
Same author

The potential role of intraovarian factors on ovarian androgen production.

Annals of the New York Academy of Sciences·2000
Same author

Leiomyoma of the uterus with massive lymphoid infiltration simulating lymphoma. A case report.

European journal of gynaecological oncology·1999
Same author

The predictive value of double Gn-RH provocation test in unprimed Gn-RH-primed and steroid-primed female patients with Kallmann's syndrome.

International journal of fertility and women's medicine·1999
Same author

Evaluation of ovarian cysts following GnRH-a treatment in patients with polycystic ovarian syndrome.

Gynecologic and obstetric investigation·1998

Area of Science:

  • Immunology
  • Endocrinology
  • Reproductive Biology

Background:

  • Emerging evidence highlights the intricate communication between the immune and endocrine systems.
  • Cytokines secreted by immune cells modulate hormone release from the hypothalamic-pituitary-adrenal (HPA) and hypothalamic-pituitary-ovarian (HPO) axes.
  • Conversely, adrenal and ovarian hormones impact cytokine production by immune cells.

Purpose of the Study:

  • To elucidate the bidirectional communication between immune and endocrine systems.
  • To understand the role of cytokines and steroid hormones in regulating each other's secretion.
  • To explore local interactions within the ovary.

Main Methods:

  • Review of existing literature on neuroendocrine-immune interactions.
  • Analysis of studies investigating cytokine and hormone signaling pathways.
  • Examination of paracrine and autocrine mechanisms in endocrine organs.

Main Results:

  • Immune-derived cytokines can inhibit or stimulate hormone secretion from the HPA and HPO axes.
  • Endocrine hormones from the adrenal glands and ovaries influence immune cell cytokine production.
  • Local ovarian interactions involve cytokines affecting follicular and luteal function, and steroidogenesis.
  • Ovarian steroids modulate cytokine secretion from resident macrophages and local endocrine cells.

Conclusions:

  • The immune and endocrine systems engage in complex, reciprocal signaling.
  • This crosstalk occurs both systemically and locally, particularly within the ovary.
  • Understanding these interactions is crucial for comprehending reproductive health and immune function.

Related Experiment Videos